QuickView for Pp2B 14D;jsessionid=2B74423D88A91C4FD35FBC0499F87FBA (gene)

Gene Symbol:

Ppp3ca Rattus norvegicus

Full name:

protein phosphatase 3 catalytic subunit alpha

Synonyms:

Calna1, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calcineurin subunit A alpha, calmodulin-dependent calcineurin A subunit alpha isoform, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform, protein phosphatase 3, catalytic subunit, alpha isoform, protein phosphatase 3, catalytic subunit, alpha isozyme, protein phosphatase-2Ba

Genomic Location:

Chr 2: 234130176-234409232

Description:

catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+/CaM-dependent protein phosphatase; mediates activities of transcription factors and ion channels; involved in regulation of T-cell activation

catalytic subunit of Calcineurin (CaN), ubiquitously expressed Ca2+/CaM-dependent protein phosphatase; mediates activities of transcription factors and ion channels; involved in regulation of T-cell activation

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Orthologs:

Homo sapiens ,  Mus musculus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAAYRNCTG_UNKNOWN ,  P300_01 ,  NFKB_C ,  WHN_B ,  ZF5_B ,  TGIF_01 ,  MEIS1_01 ,  PAX2_02 ,  MTF1_Q4 ,  SMAD4_Q6 ,  ELF1_Q6 ,  EGR_Q6 ,  AP4_Q6_01 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  AAGTCCA_MIR422B_MIR422A ,  CACTTTG_MIR520G_MIR520H ,  GTGGGTGK_UNKNOWN ,  CTATGCA_MIR153 ,  GTTTGTT_MIR495 ,  GCTTGAA_MIR498 ,  CTTTGTA_MIR524 ,  TTTGTAG_MIR520D ,  ATAAGCT_MIR21 ,  AGTCTTA_MIR499 ,  AACTGGA_MIR145 ,  TTTTGAG_MIR373 ,  CAGCACT_MIR5123P ,  RYTGCNWTGGNR_UNKNOWN ,  TTTNNANAGCYR_UNKNOWN ,  CAGCTG_AP4_Q5 ,  RTAAACA_FREAC2_01 ,  MGGAAGTG_GABP_B ,  GGGAGGRR_MAZ_Q6 ,  TGACAGNY_MEIS1_01 ,  GCANCTGNY_MYOD_Q6 ,  GGATTA_PITX2_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-21 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-378* ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-499 ,  Predicted Gene Targets for miR-543

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